Fibromyalgia (FM) is a disorder of centrally amplified and maintained musculoskeletal pain with evidence of altered pain processing in the spinal cord and brain. Although pain is the defining symptom of FM, fatigue, unrefreshing sleep, dyscognition, depression, and anxiety also have a significant impact on health-related quality of life. It is important to identify FM in order to develop an overall treatment plan that addresses the different mechanisms responsible for musculoskeletal pain.
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